Solution NMR of membrane proteins in bilayer mimics: Small is beautiful, but sometimes bigger is better

Is bigger better for primary care groups and trusts? Small can be beautiful and effective.

http://bmj.com/cgi/content/full/322/7286/599 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/322/7286/599/DC1 "Details of literature search" References http://bmj.com/cgi/content/full/322/7286/599#otherarticles 5 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/322/7286/599#BIBL This artic...

Medical data debates: big is better? Small is beautiful?

Is bigger better?

What is medical science all about? Surely it is about the value chain, which begins with basic research and ends—if there is an end— with a useful product. There is a widespread perception that scientists do a lot of basic research, but neglect the application of their findings. To remedy this, a number of organizations and philanthropists have become dedicated advocates of applied or translati...

Sometimes, more is better.

(See the article by El Sahly et al, on pages 703–12.) Influenza causes significant morbidity and mortality with an estimated 36 000 attributable deaths in the United States annually [1]. Human immunodefi-ciency virus (HIV) infection, specifically , advanced disease (CD4 count ,200 cells/lL), has been associated with excess morbidity and mortality [2]. With the use of combination antiretroviral ...

Predicting restenosis: bigger is better but not best.

The ability to accurately predict restenosis after angioplasty continues to be elusive, despite two decades of clinical and angiographic studies. Although these studies have shown that a number of clinical, procedural, and angiographic factors are related to recurrence of the stenosis, the overall predictive value of these factors remains low.1 Angiographic factors have been most extensively st...